Pharmacology

University of Manchester
Undergraduate PhD Full-time 36 Months Pharmacy, pharmacology, and toxicology

About this course

Our PhD/MPhil Pharmacology programme enables you to undertake a research project that will improve understanding of Pharmacology.

Our pharmacology research focuses on a range of topics. These include:

  • The pharmacology of drug efflux transporters, particularly ABCB1 P-glycoprotein, ABCG2 breast cancer resistance protein and ABCC multidrug resistance-associated transporters;

  • Developing complex, physiologically-relevant in vitro cell systems to investigate transport, metabolism and delivery of therapeutic drugs;

  • Understanding the pharmacological and molecular mechanisms that regulate expression and function of drug efflux transporters, particularly in the blood-brain barrier;

  • The role of blood-brain barrier drug efflux transporters in drug delivery to the central nervous system and the effects of inflammatory and degenerative conditions, e.g. Alzheimer's disease, on efflux transporter function;

  • The biological role of lipid networks in health and disease, particularly their roles in inflammation, cellular communications and tissue responses;

  • Employing mass spectrometry-based lipidomic technology, in conjunction with functional, metabolic and signalling approaches to characterise lipid profiles in physiological and pathophysiological conditions;

  • Investigating the role of lipids in skin homeostasis and in response to inflammation, injury and wound healing;

  • Studying role of local hormones in diseases and conditions associated with the female reproductive tract (e.g. dysmenorrhoea, endometriosis and the detection and prevention of preterm labour);

  • Molecularly identifying and pharmacologically characterising receptors expressed in the female reproductive system;

  • Understanding the physiological and pharmacological characteristics of the placenta. These studies include the development of placental homing peptide-microRNA inhibitor conjugates for targeted enhancement of placental growth signalling.
  • Study Options

    This course is available in 4 study options:

    Part-time

    Duration: 72 Months

    Qualification: PhD

    Location: Manchester

    Full-time Shown above

    Duration: 36 Months

    Qualification: PhD

    Location: Manchester

    Part-time

    Duration: 48 Months

    Qualification: MPhil

    Location: Manchester

    Full-time Shown above

    Duration: 12 Months

    Qualification: MPhil

    Location: Manchester

    Career Prospects

    Graduates from this course typically go into the following occupations:

    3111 Laboratory technicians
    2111 Chemical scientists
    3219 Health associate professionals
    3115 Quality assurance technicians
    2113 Biochemists and biomedical scientists
    2112 Biological scientists

    Course Details

    Qualification
    Doctor of Philosophy - PhD
    Study Mode
    Full-time
    Duration
    36 Months
    Start Date
    2025
    Academic Year
    2025
    Campus / Location
    Manchester
    Scheme
    Undergraduate
    Subjects
    Pharmacy, pharmacology, and toxicology